Total cholinesterase activity in people using pesticides in La Brea, Lepaterique during 2015

Authors

  • Alba Ruth Blanco Beneficiarios de una beca básica de la DICYP, profesores e instructores del Departamento de Control Químico, Facultad de Química y Farmacia, UNAH
  • Henry Daniel Ponce Beneficiarios de una beca básica de la DICYP, profesores e instructores del Departamento de Control Químico, Facultad de Química y Farmacia, UNAH
  • Nahúm Alcides Lanza Beneficiarios de una beca básica de la DICYP, profesores e instructores del Departamento de Control Químico, Facultad de Química y Farmacia, UNAH
  • Heydi Joseline Velásquez Beneficiarios de una beca básica de la DICYP, profesores e instructores del Departamento de Control Químico, Facultad de Química y Farmacia, UNAH
  • Gina Lucila Calderón Beneficiarios de una beca básica de la DICYP, profesores e instructores del Departamento de Control Químico, Facultad de Química y Farmacia, UNAH

DOI:

https://doi.org/10.5377/rct.v0i19.4276

Keywords:

cholinesterase, potentiometric method, pesticides

Abstract

The activity levels of the enzyme cholinesterase in whole blood of the population of La Brea, Lepaterique settled using the Michel potentiometric method. Prior to the acquisition of blood samples, a survey was applied to explore the practices and care in handling pesticides on the part of the population. Habits and application security measures, while being in contact with these products. By the results of the determination of enzyme activity in exposed and unexposed people, it is considered normal greater than or equal to 154 units of pH/hour value, using the standard deviation of the results achieved statistically determine cutoff values to indicate an inhibition in the activity of the enzyme in blood. Thus it was obtained as cutoff to establish a slight inhibition at 133 units of pH/hour value, and finally those values less than 120 units of pH/hour moderate inhibition. Of the 95 persons evaluated only three of them had lower values within the range of moderate inhibition. Finally, the results were presented to the community, as well as a quick guide for the use, management and care in the use of pesticides.

Revista Ciencia y Tecnología No.19, diciembre 2016, 94-110

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Published

2017-06-11

How to Cite

Blanco, A. R., Ponce, H. D., Lanza, N. A., Velásquez, H. J. and Calderón, G. L. (2017) “Total cholinesterase activity in people using pesticides in La Brea, Lepaterique during 2015”, Jornual of Science and Technology, (19), pp. 94–110. doi: 10.5377/rct.v0i19.4276.

Issue

Number 19, December 2016

Section

Life Sciences and Health

License

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